Cartilage’s Early Warning Signs of Arthritis

Cartilage’s Early Warning Signs of Arthritis

Even before people feel the pain of arthritis, the makeup of cartilage has been changed and can be used as an early warning sign. A study from Biophysical Journal released last month showed that damage to cartilage that occurs in the early stages of arthritis reduces its ability to “absorb shock” and depletes fluid. This damage is the result of the loss of a molecule called glycosaminoglycans (GAGs). Researchers studied the difference between GAG-depleted cartilage and normal cartilage using atomic-force-microscopy-based wide-frequency rheology system. The reduction in GAGs reduced the ability of the cartilage to withstand high-impact activities such as running and jumping. Read the news release here Cartilage May Give Early Warning of Arthritis.